Vex Rune is a high rune used in the runewords Flickering Flame, Heart of the Oak, Exile, Phoenix (Weapon), Phoenix (Shield), Destruction, Death, Breath of the Dying, Silence.
The Vex Rune can also be used as ingredient for 2 different Horadric Cube recipes.
Vex Rune like any other Diablo 2 Resurrected (D2R) Rune can be used to enhance a Socketed Item with new magical properties.
If socketed in Weapon the item will gain 7% Mana stolen per hit. When socketed in Armor, Helm, Shield it will get +5% to Maximum Fire Resist.
The fastest way to get this rune on Battle.net is via trading, you can use the Item Price Checker to see how much Vex Rune is worth.
Farming this rune by killing monsters is possible, check the drop rate table below for more information.
Another way to get it is via a horadric cube recipe that transmutes Gul runes into Vex Rune.
Unfortunately, this rune does not drop from Hell's Forge Quest.
There are 9 runewords that can be made with Vex Rune. You can also browse these Runewords in the Item Database.
There are 2 recipes that are related to Vex Rune. You can also see these Recipes in the Item Database.
The monster with the highest drop chance of dropping Vex Rune is Andariel on Hell difficulty in Catacombs Level 4 of Act 1. Farming the monsters listed below gives you the highest chance of getting that rune.