Malice is a Runeword "IthElEth" in Diablo 2 Resurrected (D2R). It requires these 3 runes to be inserted into a socketed item in the exact order: Ith + El + Eth . The eligible bases for Malice are the following: Axes, Assassin Claws, Clubs, Maces, Daggers, Polearms, Hammers, Scepters, Swords, Staves, Spears, Amazon Spears . An important benefit coming from Malice:
  • Opening wounds will cause the enemies to bleed over time. This is helpful against the Diablo clone.
This is the only Runeword in the game that has -X to Monster Defense Per Hit attribute.
Ith · El · Eth
One-Hand Damage: 1 to 40
Durability: 30 of 30
Required Dexterity: 35
Required Strength: 41
Required Level: 15
Increased Melee Range: 2
Base Attack Speed: -10
+33% Enhanced Damage
+9 to Maximum Damage
+100% Chance of Open Wounds
-25% Target Defense
-100 to Monster Defense Per Hit
Prevent Monster Heal
+50 to Attack Rating
Drain Life -5
Socketed (3)
Trade items on d2trader.net

How to obtain Malice

The fastest way to get this item on Battle.net is via trading, you can use the Item Price Checker to see how much Malice is worth.
Another way of getting this Runeword is by farming the runes and the base. Find the drop rates of these items in the Item Database.

Malice bases

The best base for Malice is Flail. Below is a list of all eligible 3 socket bases for Malice.