Sanctuary is a Runeword "KoKoMal" in Diablo 2 Resurrected (D2R). It requires these 3 runes to be inserted into a socketed item in the exact order: Ko + Ko + Mal . The eligible bases for Sanctuary are the following: Shields, Paladin Shields . There are 2 important benefits coming from Sanctuary:
  • The character will be more resistant to any elemental damage.
  • A huge dexterity boost.
SanctuarySanctuaryTroll Nest
Ko · Ko · Mal
Defense: 400 - 452
Chance To Block: (70/65/60)%
Smite Damage: 24 to 38
Durability: 74 of 74
Required Strength: 106
Required Level: 57
+20% Faster Hit Recovery
+20% Faster Block Rate
20% Increased Chance of Blocking
+(130 - 160)% Enhanced Defense
+250 Defense Vs. Missile
+20 to Dexterity
All Resistances +(50 - 70)
Magic Damage Reduced by 7
Level 12 Slow Missiles (60/60 Charges)
Socketed (3)
Trade items on d2trader.net

How to obtain Sanctuary

The fastest way to get this item on Battle.net is via trading, you can use the Item Price Checker to see how much Sanctuary is worth.
Another way of getting this Runeword is by farming the runes and the base. Find the drop rates of these items in the Item Database.

Sanctuary bases

The best base for Sanctuary is Troll Nest. Below is a list of all eligible 3 socket bases for Sanctuary.