Smoke is a Runeword "NefLum" in Diablo 2 Resurrected (D2R). It requires these 2 runes to be inserted into a socketed item in the exact order: Nef + Lum . The eligible bases for Smoke are the following: Body Armors . An important benefit coming from Smoke:
  • The character will be more resistant to any elemental damage.
SmokeSmokeDusk Shroud
Nef · Lum
Defense: 819
Durability: 20 of 20
Required Strength: 77
Required Level: 49
+75% Enhanced Defense
+280 Defense Vs. Missile
All Resistances +50
+20% Faster Hit Recovery
Level 6 Weaken (18/18 Charges)
+10 to Energy
-1 to Light Radius
Socketed (2)
Trade items on d2trader.net

How to obtain Smoke

The fastest way to get this item on Battle.net is via trading, you can use the Item Price Checker to see how much Smoke is worth.
Another way of getting this Runeword is by farming the runes and the base. Find the drop rates of these items in the Item Database.

Smoke bases

The best base for Smoke is Dusk Shroud. Below is a list of all eligible 2 socket bases for Smoke.